i have been working on this for awhile and it is still a work in progress it ties into Davids post a few days ago
hippocampus
  hippocampus
I've just been  studing that area of the brain and how cortisol (stress hormone) affects it in  the developing or infant brain.. when cortisol levels are high for to long it  starts to effect the hippocampus (brown and harris1978), infants and young  children who's brains have been flooded with cortisol tend to have smaller  hippocampi (bremner etal 1997; villareal and king 2001) adults sufferering from  depressiion also have smaller  hippocampus prehaps as a result of early  experiences,
  also the hippocampus  through its link with the orbitofrontal cortex can evaluate situations and  anticipate outcome, (if i do this this will happen and so on) a sence of  responsibility.
  high cortisol  inearly life may also be responsible for hippocampus damage,(or lack of growth  to its fullest potential),since cortisol increases the release of glutamates  which damage the hippocampus, these glutamates .  (see below for study ive done  on glutamates in foods we eat) these glutamates may interfere  with feedback systems and with the adaptability of the brain.Timing also does  seem to play an important part in setting the baseline level or cortisol  reaactivity, a childs brain is developing the most up to the age of 3,  
  (lyons et al. 2000b;  Dettling et al 2002) the afeects of early stress appear to have the potentail  for considerable handicapping of the indervidual's capacities to respond to  future stress, where behavoir such as anxiety, neurosis or depression,  borderline personality disorders etc.
  what cause high  cortisol levels in infants? as Jon Allan put in "unresponsiveness when the  infant is in a state of high attachment needs'(allan 2001)
  -an infant/child,  whose brain and body systems are still in a process of development, they can not  survive alone and are highly dependent on adults to provide for there basic  needs both phsical needs , for food, shelter, clothes etc but also emotional  needs comfort, feeling of worth, feeling loved and accepted, security/trust in  that his/her needs will be meet..
  Without these needs  meet the infant will be in a state of stress/trauma, with cortisol level high  ,
  -Trauma causes the  infant brain to be saturated in cortisol. 
  The essentail aspect  of trauma is that it generates doubts about surviving -either as a body, but  equally as a phychological self,
  what causes "trauma"  in the mind of an infant. The fear of abandonment, as when the cant see, touch  or hear their mother.(or attachment figure) and that  they will no longer have  there physical needs for food etc responed to. 
     How  does  MSG, hydrolyzed vegetable protein, and aspartame  and  neotame (which is banned from  most contrys but not NZ ).  affect the brain escpecially the  hippocampus 
  these products are called excitotoxin
   So, what is an excitotoxin? These  are substances, usually acidic amino acids, that react with specialized  receptors in the brain in such a way as to lead to destruction of certain types  of neurons. Glutamate is one of the more commonly known excitotoxins. MSG is the  sodium salt of glutamate ,
   "We can get into  trouble, however, when too much glutamate or aspartate is ingested from our food  or under certain conditions released by the brain itself (as that of the  developing brain of a child). Especially vulnerable are areas of the brain  called the hypothalamus and the hippocampus. Hypothalamic injury disrupts the  endocrine system, leading to low levels of growth hormone, thyroid hormone, the  sex hormones and the adrenal hormones. Hippocampal injury affects memory and  emotions. But other brain cells are also injured—in the cortex, the cerebellum  and a special emotional control system called the amygdala. Even the spinal cord  can be damaged."
    " What makes babies different is that  their brains are undergoing rapid development, especially during the last three  months of pregnancy and the first two years after birth. Excess glutamate and  other excitotoxins have been shown to alter how the brain is formed, leading to  varying degrees of brain maldevelopment, from mild behavioral and learning  problems to full-blown ADD, ADHD or autism.  " 
   Dr.  Russell Blaylock is a board certified neurosurgeon and a former clinical  assistant professor of neurosurgery.  
      
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